As Node.js doesn’t support for multithreaded programming, so it is not suitable for complex and large applications development. Python is simple and expressive, so it is best to be used for hosting of things and feasible choice for dealing with complex and large multi-protocol network applications.
Result: Python is suitable for developing both small and large scale development projects while Node.js is perfect for dealing with initial phase projects.
Interaction with other languages
Node.js relies heavily on JavaScript run environment, so it doesn’t offer too much integration and compatibility support with the third party programming languages. On the other side, a lot of third party modules are available for the Python that’s why it easily interact with other programming languages.
Result: Python offers a greater amount of compatibility.
Programming, Development, and Java
Node.js performance is fast in Java in run time environment because it relies heavily on it. However, Python performance is not better when it is about dealing with Java. Moreover, it is also not perfect for memory intensive projects.
Result: For integration and compatibility with Java and JavaScript, Node.js is perfect than Python.
High-End Games and Graphics
Node.js is particularly designed for dealing with the high-end game and graphical development projects. It even works on those projects as well that requires a lot of CPU activity. Python on the other end is not good in both cases.
Result: Node.js is suitable for dealing with those projects that are easy to manage on PC with low specs.
Tutorials and Helping Material
Python has one of the largest and most comprehensive standard libraries. It is offering too many guidelines and helping material. Node.js is little new, and limited examples and codes are available over the source code offering websites.
Result: Python is easy to learn because of availability of too much learning material.